Dataset Information

Surgery for weight loss in adults.

ABSTRACT:

SUBMITTER: Colquitt JL

PROVIDER: S-EPMC9028049 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature

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Surgery for weight loss in adults.

Colquitt Jill L JL Pickett Karen K Loveman Emma E Frampton Geoff K GK

The Cochrane database of systematic reviews 20140808 8

<h4>Background</h4>Bariatric (weight loss) surgery for obesity is considered when other treatments have failed. The effects of the available bariatric procedures compared with medical management and with each other are uncertain. This is an update of a Cochrane review first published in 2003 and most recently updated in 2009.<h4>Objectives</h4>To assess the effects of bariatric surgery for overweight and obesity, including the control of comorbidities.<h4>Search methods</h4>Studies were obtained ...[more]

PMID: 25105982

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Project description:Objectives: To investigate the impact of the Cambridge Intensive Weight Management Programme (IWMP) on weight change, eligibility for bariatric surgery, HbA1c, and blood pressure. Design: Prospective non-randomized intervention. Setting: The IWMP is a multi-disciplinary weight loss intervention for severely obese patients to avoid or optimize their physiological state thus enabling bariatric surgery. It uses dietary interventions, pharmacotherapy, and physical activity along with behavior change counseling. Participants: Severely obese patients (Body Mass Index, BMI≥40 kg/m2). Interventions: IWMP is a prospective intervention conducted in a National Health Service Tier 3 obesity service. It includes 3 phases of 8 weeks each: weight loss, weight stabilization, and weight maintenance. In each phase, patients adhered to a prescribed dietary regime and attended regular clinic visits. Data included in this analysis are from those who enrolled in IWMP between 2009 and 2013. Primary and secondary measures: The primary outcome was weight change between baseline and completion of the programme. Secondary outcomes included changes in blood pressure, HbA1c and eligibility for bariatric surgery pre-assessment. Changes in outcomes were compared by age, sex, smoking status, and employment. Results: Of n = 222 eligible patients, complete data were available for n = 141 patients (63.5%). At baseline, the mean (SD) BMI was 49.7 (9.2) kg/m2 for women, and 47.9 (7.2) kg/m2 for men. Mean (SD) weight change for women was -18.64 (8.36) kg and -22.46 (10.98) kg for men. N = 97 (69%) of patients achieved ≥10% weight loss. Individuals aged ≤ 50 years lost significantly more weight than those aged >50 years [mean (SD) weight loss: 22.18 (10.9) kg vs. 18.32 (7.92) kg, p = 0.020]. Changes in weight were non-significant by smoking status or employment. Median (IQR) change in systolic and diastolic blood pressure was -6 (-14.6) mmHg and 0 (-8.6) mmHg (non-significant), respectively. There was ~50% reduction in the need for bariatric surgery. Conclusions: For the majority of the patients, IWMP is promoting weight loss and allowing for avoidance of, or optimization before, bariatric surgery.

Dataset Information

Surgery for weight loss in adults.

Publications

Surgery for weight loss in adults.

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