Mutation in 23S rRNA responsible for resistance to 16-membered macrolides and streptogramins in Streptococcus pneumoniae.
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ABSTRACT:
SUBMITTER: Depardieu F
PROVIDER: S-EPMC90283 | biostudies-literature | 2001 Jan
REPOSITORIES: biostudies-literature
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Mutation in 23S rRNA responsible for resistance to 16-membered macrolides and streptogramins in Streptococcus pneumoniae.
Antimicrobial agents and chemotherapy 20010101 1
Streptococcus pneumoniae clinical isolate BM4455 was resistant to 16-membered macrolides and to streptogramins. This unusual resistance phenotype was due to an A(2062)C (Escherichia coli numbering) mutation in domain V of the four copies of 23S rRNA. ...[more]
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