Ontology highlight
ABSTRACT:
SUBMITTER: Suschak JJ
PROVIDER: S-EPMC9033795 | biostudies-literature | 2022 Apr
REPOSITORIES: biostudies-literature
Suschak John J JJ Bixler Sandra L SL Badger Catherine V CV Spik Kristin W KW Kwilas Steven A SA Rossi Franco D FD Twenhafel Nancy N Adams Melissa L ML Shoemaker Charles J CJ Spiegel Erin E Hooper Jay W JW
NPJ vaccines 20220422 1
We have previously shown that DNA vaccines expressing codon optimized alphavirus envelope glycoprotein genes protect both mice and nonhuman primates from viral challenge when delivered by particle-mediated epidermal delivery (PMED) or intramuscular (IM) electroporation (EP). Another technology with fewer logistical drawbacks is disposable syringe jet injection (DSJI) devices developed by PharmaJet, Inc. These needle-free jet injection systems are spring-powered and capable of delivering vaccines ...[more]