Ontology highlight
ABSTRACT:
SUBMITTER: Major A
PROVIDER: S-EPMC9036549 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Major Ajay A Smith Sonali M SM
Clinical advances in hematology & oncology : H&O 20211101 11
The emerging molecular and prognostic characterization of diffuse large B-cell lymphoma (DLBCL) has challenged the rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) treatment paradigm in recent years, with the identification of several DLBCL subtypes associated with significantly inferior survival after standard R-CHOP therapy. Efforts to improve upon the R-CHOP backbone have included dose intensification as well as the addition of new agents; the infusional dose-adj ...[more]