Ontology highlight
ABSTRACT:
SUBMITTER: Siti Sarah CO
PROVIDER: S-EPMC9037125 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Siti Sarah Che Othman CO Nur Husna Siti Muhamad SM Md Shukri Norasnieda N Wong Kah Keng KK Mohd Ashari Noor Suryani NS
PeerJ 20220422
Allergic rhinitis (AR) is a common allergic disease characterized by disruption of nasal epithelial barrier. In this study, we investigated the mRNA expression of zonula occludens-1 (<i>ZO-1</i>), <i>ZO-2</i> and <i>ZO-3</i> and histone deacetylase 1 (<i>HDAC1</i>) and <i>HDAC2</i> in AR patients compared to healthy controls. RNA samples were extracted from nasal epithelial cells of house dust mites (HDMs)-sensitized AR patients and healthy controls (<i>n</i> = 28 in each group). The RNAs were r ...[more]