SARS-CoV-2 infection in the first trimester and the risk of early miscarriage: a UK population-based prospective cohort study of 3041 pregnancies conceived during the pandemic.
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ABSTRACT:
SUBMITTER: Balachandren N
PROVIDER: S-EPMC9047154 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
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SARS-CoV-2 infection in the first trimester and the risk of early miscarriage: a UK population-based prospective cohort study of 3041 pregnancies conceived during the pandemic.
Balachandren Neerujah N Davies Melanie C MC Hall Jennifer A JA Stephenson Judith M JM David Anna L AL Barrett Geraldine G O'Neill Helen C HC Ploubidis George B GB Yasmin Ephia E Mavrelos Dimitrios D
Human reproduction (Oxford, England) 20220501 6
<h4>Study question</h4>Does maternal infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the first trimester affect the risk of miscarriage before 13 week's gestation?<h4>Summary answer</h4>Pregnant women with self-reported diagnosis of SARS-CoV-2 in the first trimester had a higher risk of early miscarriage.<h4>What is known already</h4>Viral infections during pregnancy have a broad spectrum of placental and neonatal pathology. Data on the effects of the SARS-CoV-2 in ...[more]
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