Ontology highlight
ABSTRACT:
SUBMITTER: Puchenkova OA
PROVIDER: S-EPMC9052234 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Puchenkova Olesya A OA Soldatov Vladislav O VO Belykh Andrei E AE Bushueva OlgaYu O Piavchenko Gennadii A GA Venediktov Artem A AA Shakhpazyan Nikolay K NK Deykin Alexey V AV Korokin Mikhail V MV Pokrovskiy Mikhail V MV
Biomarker insights 20220425
Abdominal aortic aneurysm (AAA) is a potentially life-threatening disorder with a mostly asymptomatic course where the abdominal aorta is weakened and bulged. Cytokines play especially important roles (both positive and negative) among the molecular actors of AAA development. All the inflammatory cascades, extracellular matrix degradation and vascular smooth muscle cell apoptosis are driven by cytokines. Previous studies emphasize an altered expression and a changed epigenetic regulation of key ...[more]