Ontology highlight
ABSTRACT:
SUBMITTER: Yousfan A
PROVIDER: S-EPMC9055806 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Yousfan Amal A Rubio Noelia N Natouf Abdul Hakim AH Daher Aamal A Al-Kafry Nedal N Venner Kerrie K Kafa Houmam H
RSC advances 20200805 48
The use of nanoparticles (NPs) for intranasal (IN) drug delivery to the brain represents a hopeful strategy to enhance brain targeting of anti-epileptic drugs. In the present work, chitosan-lecithin NPs loaded with phenytoin (PHT), were prepared using the nano-precipitation method. The spherical nature of the NPs and their stability were confirmed using scanning and transmission electron microscopy, while the average dynamic size and zeta potential were measured using dynamic light scattering. T ...[more]