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Sequences of the NPS-1 and TLE-1 beta-lactamase genes.


ABSTRACT: The NPS-1 and TLE-1 beta-lactamase genes were cloned and sequenced. NPS-1 differed from LCR-1 beta-lactamase in 8 of 260 amino acids. TLE-1 differed from TEM-1 by a single Asp(115)-->Gly substitution and has been renamed TEM-90.

SUBMITTER: Pai H 

PROVIDER: S-EPMC90761 | biostudies-literature | 2001 Oct

REPOSITORIES: biostudies-literature

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Sequences of the NPS-1 and TLE-1 beta-lactamase genes.

Pai H H   Jacoby G A GA  

Antimicrobial agents and chemotherapy 20011001 10


The NPS-1 and TLE-1 beta-lactamase genes were cloned and sequenced. NPS-1 differed from LCR-1 beta-lactamase in 8 of 260 amino acids. TLE-1 differed from TEM-1 by a single Asp(115)-->Gly substitution and has been renamed TEM-90. ...[more]

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