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Preparation of a mimetic and degradable poly(ethylene glycol) by a non-eutectic mixture of organocatalysts (NEMO) via a one-pot two-step process.

ABSTRACT: A one-pot, two-step method for the preparation of degradable PEG is here presented. The full process addresses the requirements imposed by green chemistry and involves the use of a single and nontoxic non-eutectic mixture of organocatalysts. The strategy relies on the polycondensation of PEG800 after its functionalization by bio-derived 5-membered γ-butyrolactone.

SUBMITTER: Moins S

PROVIDER: S-EPMC9076182 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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Preparation of a mimetic and degradable poly(ethylene glycol) by a non-eutectic mixture of organocatalysts (NEMO) <i>via</i> a one-pot two-step process.

Moins S S Loyer P P Odent J J Coulembier O O

RSC advances 20191204 68

A one-pot, two-step method for the preparation of degradable PEG is here presented. The full process addresses the requirements imposed by green chemistry and involves the use of a single and nontoxic non-eutectic mixture of organocatalysts. The strategy relies on the polycondensation of PEG800 after its functionalization by bio-derived 5-membered γ-butyrolactone. ...[more]

PMID: 35541396

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