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Indication of transposition of a mobile DNA element containing the vat(D) and erm(B) genes in Enterococcus faecium.

ABSTRACT: The vat(D) and erm(B) genes encoding streptogramin resistance in Enterococcus faecium transferred together, and a direct physical link between erm(B) and vat(D) was detected. Both the vat(D) and erm(B) probes hybridized to fragments of different sizes in the donor and transconjugants, which indicated a transposition event.

SUBMITTER: Hammerum AM

PROVIDER: S-EPMC90811 | biostudies-literature | 2001 Nov

REPOSITORIES: biostudies-literature

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Indication of transposition of a mobile DNA element containing the vat(D) and erm(B) genes in Enterococcus faecium.

Hammerum A M AM Flannagan S E SE Clewell D B DB Jensen L B LB

Antimicrobial agents and chemotherapy 20011101 11

The vat(D) and erm(B) genes encoding streptogramin resistance in Enterococcus faecium transferred together, and a direct physical link between erm(B) and vat(D) was detected. Both the vat(D) and erm(B) probes hybridized to fragments of different sizes in the donor and transconjugants, which indicated a transposition event. ...[more]

PMID: 11600385

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