Ontology highlight
ABSTRACT:
SUBMITTER: Tsuge K
PROVIDER: S-EPMC90870 | biostudies-literature | 2001 Dec
REPOSITORIES: biostudies-literature
Antimicrobial agents and chemotherapy 20011201 12
Surfactin is a cyclic lipopeptide biosurfactant. Transposon mutagenesis was performed in Bacillus subtilis strain 168, and a surfactin-susceptible mutant, strain 801, was isolated. Analysis of the region of insertion revealed that yerP was the determinant of surfactin self-resistance. YerP had homology with the resistance, nodulation, and cell division (RND) family proton motive force-dependent efflux pumps only characterized in gram-negative strains. The yerP-deficient strain 802, in which the ...[more]