Ontology highlight
ABSTRACT:
SUBMITTER: Decousser JW
PROVIDER: S-EPMC90875 | biostudies-literature | 2001 Dec
REPOSITORIES: biostudies-literature
Decousser J W JW Poirel L L Nordmann P P
Antimicrobial agents and chemotherapy 20011201 12
A chromosomally located beta-lactamase gene, cloned and expressed in Escherichia coli from a reference strain of the enterobacterial species Kluyvera cryocrescens, encoded a clavulanic acid-inhibited Ambler class A enzyme, KLUC-1, with a pI value of 7.4. KLUC-1 shared 86% amino acid identity with a subgroup of plasmid-mediated CTX-M-type extended-spectrum beta-lactamases (CTX-M-1, -3, -10, -11, and -12), the most closely related enzymes, and 77% amino acid identity with KLUA-1 from Kluyvera asco ...[more]