Ontology highlight
ABSTRACT:
SUBMITTER: Trumpelmann S
PROVIDER: S-EPMC9111759 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
Trümpelmann Susan S Schulte-Mecklenbeck Andreas A Steinberg Olga V OV Wirth Timo T Fobker Manfred M Lohmann Lisa L Lünemann Jan D JD Wiendl Heinz H Gross Catharina C CC Klotz Luisa L
Clinical and translational science 20220304 7
The impact of distinct disease-modifying therapies (DMTs) on severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) vaccination efficacy in patients with multiple sclerosis (MS) is still enigmatic. In this prospective comparative study, we investigated humoral and cellular immune-responses in patients with MS receiving interferon beta, natalizumab, and ocrelizumab pre-vaccination and 6 weeks post second SARS-CoV-2 vaccination. Healthy individuals and interferon beta-treated patients genera ...[more]