Unknown

Dataset Information

0

An ecological momentary assessment study of age effects on perceptive and non-perceptive clinical high-risk symptoms of psychosis.


ABSTRACT: Among individuals with clinical high risk for psychosis (CHR), perceptive symptoms are more frequent but have less clinical significance in children/adolescents compared to adults. However, findings are based on clinical interviews relying on patient's recall capacity. Ecological momentary assessment (EMA) can be used to explore experiences in real-time in the subject's daily life. The aim of this study was to assess frequency and stability of (perceptive and non-perceptive) CHR symptoms and to explore potential age effects. EMA was used in a sample of an early detection for psychosis service in Bern, Switzerland (N = 66; 11-36 years). CHR symptoms were recorded in random time intervals for seven days: eight assessments per day per subject, minimum time between prompts set at 25 min. CHR symptoms were additionally assessed with semi-structured interviews including the 'Structured Interview for Psychosis-Risk Syndromes' and the 'Schizophrenia Proneness Instruments'. Mixed-effects linear regression analysis on the frequency of CHR symptoms revealed a significant effect of age group, and the interaction CHR symptoms x age group for both perceptive and non-perceptive symptoms. Further, regarding stability of CHR symptoms, there was a significant effect of the interaction CHR symptoms x age group for perceptive symptoms only. Based on EMA, perceptive CHR symptoms were more frequently reported but less stable in children/adolescents compared with adults. Together with previous findings, our finding of higher instability/variability of perceptive symptoms in younger persons might suggest that with advancing age and more stability of CHR symptoms, clinical relevance (reduced psychosocial functioning) may increase.

SUBMITTER: Michel C 

PROVIDER: S-EPMC9116495 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC3758982 | biostudies-literature
| S-EPMC8621669 | biostudies-literature
| S-EPMC5539388 | biostudies-literature
| S-EPMC5824204 | biostudies-literature
| S-EPMC9150728 | biostudies-literature
| S-EPMC5433621 | biostudies-literature
| S-EPMC8663593 | biostudies-literature
| S-EPMC10797510 | biostudies-literature
| S-EPMC3251738 | biostudies-literature
| S-EPMC11258473 | biostudies-literature