Dataset Information

Measuring serum sodium levels using blood gas analyzer and auto analyzer in heart and lung disease patients: A cross-sectional study.

ABSTRACT:

Objective

Emergency services require precise and rapid measurement of electrolytes to initiate treatment. Blood gas analyzers (BGA) analyzes blood samples in seconds however, its accuracy is still debatable. The aim of this study was to compare the level of serum sodium measured through BGA and auto analyzer in the laboratory analyzers.

Methods

This cross-sectional study was performed on 79 patients with heart and lung disease in the intensive care unit of the center. Patient information was recorded along with serum sodium levels measured through BGA and auto analyzer in the laboratory.

Results

The mean sodium level measured by BGA was 138.38 mEq/L and by auto analyzer was 137.42 mEq/L. The difference was statistically significant, p = 0.007. Among lung disease patients, the mean sodium levels from BGA and autoanalyzer did not differ significantly p = 0.052 where in patients with heart disease, these levels were 138.54 mEq/L and 137.23 mEq/L, respectively. The difference was significantly different, p = 0.015. Acidic pH measured using BGA and autoanalyzer also differed significantly, p = 0.006.

Conclusion

Blood gas analyzer method has a high correlation with laboratory analyzer, but in cases of hypernatremia, the accuracy of blood gas analyzer method decreases and especially in acidosis and in patients with pulmonary problems, the difference with laboratory method increases.

SUBMITTER: Zamanabadi MN

PROVIDER: S-EPMC9117252 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature

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Publications

Measuring serum sodium levels using blood gas analyzer and auto analyzer in heart and lung disease patients: A cross-sectional study.

Zamanabadi Mahnaz Narimani MN Zamanabadi Tina Narimani TN Alizadeh Reza R

Annals of medicine and surgery (2012) 20220513

<h4>Objective</h4>Emergency services require precise and rapid measurement of electrolytes to initiate treatment. Blood gas analyzers (BGA) analyzes blood samples in seconds however, its accuracy is still debatable. The aim of this study was to compare the level of serum sodium measured through BGA and auto analyzer in the laboratory analyzers.<h4>Methods</h4>This cross-sectional study was performed on 79 patients with heart and lung disease in the intensive care unit of the center. Patient info ...[more]

PMID: 35600187

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Project description:BackgroundMindray's newly developed BC-7500 CRP auto hematology analyzers can simultaneously measure the routine blood and C-reactive protein (CRP) results, thereby significantly improving the efficiency and quality of clinical examination. This study was designed to evaluate the basic performance of the BC-7500 CRP as well as the performance characteristics of the new measurement mode combines routine blood and CRP.MethodsVenous whole blood samples with the anticoagulant ethylene diamine tetraacetic acid K2 (EDTA-K2) were collected at the Fujian Medical University Union Hospital according to the guidelines of the American Clinical Laboratory Standards Institute (CLSI) and International Standards Committee for Hematology (ISCH). We analyzed and evaluated the performance of blank counts, carryover contamination rate, precision, comparability, flagging capability, sample stability, and automatic micro-whole blood (MWB) mode analysis in the BC-7500 CRP hematology analyzer.ResultsAll parameters measured by the BC-7500 CRP showed good blank counts (CRP, 0.008-0.02 mg/L). The carryover contamination rates for each mode combination did not exceed 1%, it indicates a low carryover effect. The CRP showed high precision while the within-laboratory precision is 6.91% and 4.38% in two different levels. Relatively good correlation was found for the routine blood results between the BC-7500 CRP and Sysmex-XN (r=0.99), and CRP result between the BC-7500 CRP and IMMAGE 800 (r=0.99). The sensitivities of abnormal cell flagging for Blast, Immature Gran, and nucleated red blood cell (NRBC) were 93.9%, 91.6%, and 86.7%, while their specificities were 83.9%, 62.7%, and 97.5%. The test results of CRP at room temperature for 24 hours and refrigerated for 48 hours were -0.04% and -2.94%, which showed very stable changes. Also, the automatic micro-whole blood mode performed well (P=0.2014), which was very close to the test results of the automatic mixing test of peripheral blood and the manual mixing of open sampling.ConclusionsThe BC-7500 CRP analyzer provided reliable results on routine blood and CRP, which can meet the testing requirements of routine blood and CRP items in clinical whole blood samples and provide a guarantee for rapid and accurate laboratory diagnosis.

Dataset Information

Measuring serum sodium levels using blood gas analyzer and auto analyzer in heart and lung disease patients: A cross-sectional study.

Objective

Methods

Results

Conclusion

Publications

Measuring serum sodium levels using blood gas analyzer and auto analyzer in heart and lung disease patients: A cross-sectional study.

Similar Datasets

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