QKI-6 Suppresses Cell Proliferation, Migration, and EMT in Non-Small Cell Lung Cancer.
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ABSTRACT:
SUBMITTER: Zhang H
PROVIDER: S-EPMC9117621 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Publications
QKI-6 Suppresses Cell Proliferation, Migration, and EMT in Non-Small Cell Lung Cancer.
Zhang Haihua H Li Junqiang J Tian Feng F Su Xuan X Wang Xinxin X Tang Di D Zhang Lei L Zhang Tao T Ni Yunfeng Y
Frontiers in oncology 20220505
The RNA-binding protein quaking homolog 6 (QKI-6) is a tumor-suppressor gene in several cancers. However, its role in non-small cell lung cancer (NSCLC) is unclear. In this study, we aimed to determine the association between QKI-6 expression and survival and clinicopathological features in patients with NSCLC and identify the related mechanisms. Western blot and immunohistochemistry (IHC) were used to detect QKI-6 expression in NSCLC. The effect of QKI-6 on NSCLC cells was determined by overexp ...[more]
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