Ontology highlight
ABSTRACT:
SUBMITTER: Silva TC
PROVIDER: S-EPMC9122535 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
Silva Tiago C TC Young Juan I JI Martin Eden R ER Chen X Steven XS Wang Lily L
Nucleic acids research 20220501 9
Epigenome-wide association studies often detect many differentially methylated sites, and many are located in distal regulatory regions. To further prioritize these significant sites, there is a critical need to better understand the functional impact of CpG methylation. Recent studies demonstrated that CpG methylation-dependent transcriptional regulation is a widespread phenomenon. Here, we present MethReg, an R/Bioconductor package that analyzes matched DNA methylation and gene expression data ...[more]