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Transmission Potential of the Omicron Variant of Severe Acute Respiratory Syndrome Coronavirus 2 in South Korea, 25 November 2021-8 January 2022.

ABSTRACT: Our study indicates sustained transmission (effective reproduction number, 1.3; serial interval, 4.2 days; regional doubling times, 3.3-11.4 days) of the severe acute respiratory syndrome coronavirus 2 Omicron (B.1.1.529) variant (N = 2351) in South Korea (25 November 2021-8 January 2022), implicating insufficient protection through vaccination and supporting nonpharmaceutical control measures.

SUBMITTER: Shim E

PROVIDER: S-EPMC9129224 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature

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Transmission Potential of the Omicron Variant of Severe Acute Respiratory Syndrome Coronavirus 2 in South Korea, 25 November 2021-8 January 2022.

Shim Eunha E Choi Wongyeong W Kwon Donghyok D Kim Taeyoung T Song Youngji Y

Open forum infectious diseases 20220513 7

Our study indicates sustained transmission (effective reproduction number, 1.3; serial interval, 4.2 days; regional doubling times, 3.3-11.4 days) of the severe acute respiratory syndrome coronavirus 2 Omicron (B.1.1.529) variant (N = 2351) in South Korea (25 November 2021-8 January 2022), implicating insufficient protection through vaccination and supporting nonpharmaceutical control measures. ...[more]

PMID: 35855956

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Community Transmission of SARS-CoV-2 Omicron Variant, South Korea, 2021.

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Project description: Not available

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Probable Transmission of SARS-CoV-2 Omicron Variant in Quarantine Hotel, Hong Kong, China, November 2021.

Project description:We report detection of severe acute respiratory syndrome coronavirus 2 Omicron variant (B.1.1.529) in an asymptomatic, fully vaccinated traveler in a quarantine hotel in Hong Kong, China. The Omicron variant was also detected in a fully vaccinated traveler staying in a room across the corridor from the index patient, suggesting transmission despite strict quarantine precautions.

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Transmission dynamics of SARS-CoV-2 Omicron variant infections in Hangzhou, Zhejiang, China, January-February 2022.

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Tracking the progressive spread of the SARS-CoV-2 Omicron variant in Italy, December 2021 to January 2022.

Project description:BackgroundThe SARS-CoV-2 variant of concern Omicron was first detected in Italy in November 2021.AimTo comprehensively describe Omicron spread in Italy in the 2 subsequent months and its impact on the overall SARS-CoV-2 circulation at population level.MethodsWe analyse data from four genomic surveys conducted across the country between December 2021 and January 2022. Combining genomic sequencing results with epidemiological records collated by the National Integrated Surveillance System, the Omicron reproductive number and exponential growth rate are estimated, as well as SARS-CoV-2 transmissibility.ResultsOmicron became dominant in Italy less than 1 month after its first detection, representing on 3 January 76.9-80.2% of notified SARS-CoV-2 infections, with a doubling time of 2.7-3.3 days. As of 17 January 2022, Delta variant represented < 6% of cases. During the Omicron expansion in December 2021, the estimated mean net reproduction numbers respectively rose from 1.15 to a maximum of 1.83 for symptomatic cases and from 1.14 to 1.36 for hospitalised cases, while remaining relatively stable, between 0.93 and 1.21, for cases needing intensive care. Despite a reduction in relative proportion, Delta infections increased in absolute terms throughout December contributing to an increase in hospitalisations. A significant reproduction numbers' decline was found after mid-January, with average estimates dropping below 1 between 10 and 16 January 2022.ConclusionEstimates suggest a marked growth advantage of Omicron compared with Delta variant, but lower disease severity at population level possibly due to residual immunity against severe outcomes acquired from vaccination and prior infection.

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Molecular SARS-CoV-2 surveillance in Bavaria shows no Omicron transmission before the end of November 2021.

Project description:BackgroundFive SARS-CoV-2 variants are currently considered as variants of concern (VOC). Omicron was declared a VOC at the end of November 2021. Based on different diagnostic methods, the occurrence of Omicron was reported by 52 countries worldwide on December 7 2021. First notified by South Africa with alarming reports on increasing infection rates, this new variant was soon suspected to replace the currently pre-dominating Delta variant leading to further infection waves worldwide.MethodsUsing VOC PCR screening and Next Generation Sequencing (NGS) analysis of selected samples, we investigated the circulation of Omicron in the German federal state Bavaria. For this, we analyzed SARS-CoV-2 surveillance data from our laboratory generated from calendar week (CW) 01 to 49/2021.ResultsSo far, we have detected 69 Omicron cases in our laboratory from CW 47-49/2021 using RT-qPCR followed by melting curve analysis. The first 16 cases were analyzed by NGS and all were confirmed as Omicron.ConclusionOur data strongly support no circulation of the new Omicron variant before CW 47/2021.

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