Ontology highlight
ABSTRACT:
SUBMITTER: Zheng ZY
PROVIDER: S-EPMC9132929 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
Zheng Zhen-Yuan ZY Chu Man-Yu MY Lin Wan W Zheng Ya-Qi YQ Xu Xiu-E XE Chen Yang Y Liao Lian-Di LD Wu Zhi-Yong ZY Wang Shao-Hong SH Li En-Min EM Xu Li-Yan LY
Cell death & disease 20220525 5
Esophageal squamous cell carcinoma (ESCC) is one of the world's leading causes of death, and its primary clinical therapy relies on surgical resection, chemotherapy, radiotherapy, and chemoradiotherapy. Although the genomic features and clinical significance of ESCC have been identified, the outcomes of targeted therapies are still unsatisfactory. Here, we demonstrate that mitogen-activated protein kinase (MAPK) signaling is highly activated and associated with poor prognosis in patients with ES ...[more]