Metabolism Dysregulation in Retinal Diseases and Related Therapies.
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ABSTRACT:
SUBMITTER: Chen Y
PROVIDER: S-EPMC9137684 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
Publications
Metabolism Dysregulation in Retinal Diseases and Related Therapies.
Chen Yingying Y Coorey Nathan J NJ Zhang Meixia M Zeng Shaoxue S Madigan Michele C MC Zhang Xinyuan X Gillies Mark C MC Zhu Ling L Zhang Ting T
Antioxidants (Basel, Switzerland) 20220511 5
The human retina, which is part of the central nervous system, has exceptionally high energy demands that requires an efficient metabolism of glucose, lipids, and amino acids. Dysregulation of retinal metabolism disrupts local energy supply and redox balance, contributing to the pathogenesis of diverse retinal diseases, including age-related macular degeneration, diabetic retinopathy, inherited retinal degenerations, and Macular Telangiectasia. A better understanding of the contribution of dysre ...[more]
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