Ontology highlight
ABSTRACT:
SUBMITTER: Gray WL
PROVIDER: S-EPMC9144398 | biostudies-literature | 2022 Apr
REPOSITORIES: biostudies-literature
Viruses 20220419 5
Varicella zoster virus (VZV) and simian varicella virus (SVV) cause varicella (chickenpox) in children and nonhuman primates, respectively. After resolution of acute disease, the viruses establish latent infection in neural ganglia, after which they may reactivate to cause a secondary disease, such as herpes zoster. SVV infection of nonhuman primates provides a model to investigate VZV pathogenesis and antiviral strategies. The VZV and SVV genomes are similar in size and structure and share 70-7 ...[more]