Ontology highlight
ABSTRACT:
SUBMITTER: He M
PROVIDER: S-EPMC9149310 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
He Meihui M Rong Rong R Ji Dan D Xia Xiaobo X
Frontiers in cell and developmental biology 20220516
Glaucoma is a group of optic neuropathies featured by degeneration of retinal ganglion cells and loss of their axons in the optic nerve. The only currently approved therapies focus on lowering intraocular pressure with medication and surgery. Over the previous few decades, technological advances and research progress regarding pathogenesis has brought glaucomatous gene therapy to the forefront. In this review, we discuss the three current genome editing methods and potential disease mechanisms o ...[more]