Ontology highlight
ABSTRACT:
SUBMITTER: Caceres CJ
PROVIDER: S-EPMC9157400 | biostudies-literature | 2022 Jun
REPOSITORIES: biostudies-literature
Caceres C Joaquin CJ Seibert Brittany B Cargnin Faccin Flavio F Cardenas-Garcia Stivalis S Rajao Daniela S DS Perez Daniel R DR
FEBS open bio 20220427 6
Influenza A and B viruses are among the most prominent human respiratory pathogens. About 3-5 million severe cases of influenza are associated with 300 000-650 000 deaths per year globally. Antivirals effective at reducing morbidity and mortality are part of the first line of defense against influenza. FDA-approved antiviral drugs currently include adamantanes (rimantadine and amantadine), neuraminidase inhibitors (NAI; peramivir, zanamivir, and oseltamivir), and the PA endonuclease inhibitor (b ...[more]