Ontology highlight
ABSTRACT:
SUBMITTER: Islam MM
PROVIDER: S-EPMC9160259 | biostudies-literature | 2022 Jun
REPOSITORIES: biostudies-literature
Islam Mohammad Mirazul MM Chivu Alexandru A AbuSamra Dina B DB Saha Amrita A Chowdhuri Sumit S Pramanik Bapan B Dohlman Claes H CH Das Debapratim D Argüeso Pablo P Rajaiya Jaya J Patra Hirak K HK Chodosh James J
Scientific reports 20220601 1
Development of an artificial cornea can potentially fulfil the demand of donor corneas for transplantation as the number of donors is far less than needed to treat corneal blindness. Collagen-based artificial corneas stand out as a regenerative option, having promising clinical outcomes. Collagen crosslinked with chemical crosslinkers which modify the parent functional groups of collagen. However, crosslinkers are usually cytotoxic, so crosslinkers need to be removed from implants completely bef ...[more]