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Urban Determinants of COVID-19 Spread: a Comparative Study across Three Cities in New York State.

ABSTRACT: The ongoing pandemic is laying bare dramatic differences in the spread of COVID-19 across seemingly similar urban environments. Identifying the urban determinants that underlie these differences is an open research question, which can contribute to more epidemiologically resilient cities, optimized testing and detection strategies, and effective immunization efforts. Here, we perform a computational analysis of COVID-19 spread in three cities of similar size in New York State (Colonie, New Rochelle, and Utica) aiming to isolate urban determinants of infections and deaths. We develop detailed digital representations of the cities and simulate COVID-19 spread using a complex agent-based model, taking into account differences in spatial layout, mobility, demographics, and occupational structure of the population. By critically comparing pandemic outcomes across the three cities under equivalent initial conditions, we provide compelling evidence in favor of the central role of hospitals. Specifically, with highly efficacious testing and detection, the number and capacity of hospitals, as well as the extent of vaccination of hospital employees are key determinants of COVID-19 spread. The modulating role of these determinants is reduced at lower efficacy of testing and detection, so that the pandemic outcome becomes equivalent across the three cities.

SUBMITTER: Truszkowska A

PROVIDER: S-EPMC9170119 | biostudies-literature |

REPOSITORIES: biostudies-literature

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Project description:Interest in nature-based approaches for climate change adaptation in cities is growing. Whilst there is a growing field of scholarship in a European and North America setting, research on the policy and governance of urban greenspace for climate adaptation in subtropical Asia is limited. Given the different development patterns, environmental characteristics and governance arrangements in subtropical cities, plus their comparatively large population and high climate risk, this is a significant knowledge gap. In response, this paper evaluates competences - skill sets, capabilities, and supporting policy and legislation - to enact adaptation through greenspace across different governance contexts; and assesses how international rhetoric on nature-based adaptation becomes localised to subtropical Asian city settings. We conduct interviews with stakeholders, plus review of relevant policy and city-specific research, for three cities with different governance and development contexts: Hanoi (Vietnam); Taipei (Taiwan); and Fukuoka (Japan). Across all three cases, we find that institutional structures and processes for connecting different remits and knowledge systems are a bigger challenge than a lack of appropriate policy or individuals with the required technical knowledge. However, opportunities for civil society participation and consideration of justice issues vary between the cities according to the socio-political context. These findings illustrate the value of individuals and organisations able to work across institutional boundaries in linking greenspace and adaptation agendas for subtropical Asian cities; and the importance of competence in collaboration with developers and civil society so that the rapid development or regeneration seen in subtropical Asian contexts does not tend towards green climate gentrification. More broadly, our findings show that the diverse nature of subtropical Asian cities means the role of greenspace in climate adaptation is likely to be context-specific, and thus that caution must be exercised against uncritically importing best practices from exemplar cases elsewhere.

Project description:BACKGROUND:Previous work reported increased rates of acute cardiovascular hospitalizations associated with increased PM2.5 concentrations in the previous few days across urban centers in New York State from 2005 to 2016. These relative rates were higher after air quality policies and economic changes resulted in decreased PM2.5 concentrations and changes in PM composition (e.g. increased secondary organic carbon), compared to before and during these changes. Changes in PM composition and sources may explain this difference. OBJECTIVES:To estimate the rate of acute cardiovascular hospitalizations associated with increases in source specific PM2.5 concentrations. METHODS:Using source apportioned PM2.5 concentrations at the same NYS urban sites, a time-stratified case-crossover design, and conditional logistic regression models adjusting for ambient temperature and relative humidity, we estimated the rate of these acute cardiovascular hospitalizations associated with increases in mean source specific PM2.5 concentrations in the previous 1, 4, and 7?days. RESULTS:Interquartile range (IQR) increases in spark-ignition emissions (GAS) concentrations were associated with increased excess rates of cardiac arrhythmia hospitalizations (2.3%; 95% CI?=?0.4%, 4.2%; IQR?=?2.56??g/m3) and ischemic stroke hospitalizations (3.7%; 95% CI?=?1.1%, 6.4%; 2. 73??g/m3) over the next day. IQR increases in diesel (DIE) concentrations were associated with increased rates of congestive heart failure hospitalizations (0.7%; 95% CI?=?0.2% 1.3%; 0.51??g/m3) and ischemic heart disease hospitalizations (0.8%; 95% CI?=?0.3%, 1.3%; 0.60??g/m3) over the next day, as hypothesized. However, secondary sulfate PM2.5 (SS) was not. Increased acute cardiovascular hospitalization rates were also associated with IQR increases in concentrations of road dust (RD), residual oil (RO), and secondary nitrate (SN) over the previous 1, 4, and 7?days, but not other sources. CONCLUSIONS:These findings suggest a role of several sources of PM2.5 in New York State (i.e. traffic emissions, non-traffic emissions such as brake and tire wear, residual oil, and nitrate that may also reflect traffic emissions) in the triggering of acute cardiovascular events.

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Urban Determinants of COVID-19 Spread: a Comparative Study across Three Cities in New York State.

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