Ontology highlight
ABSTRACT:
SUBMITTER: Lee JH
PROVIDER: S-EPMC9179593 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
Lee Ji Hyun JH Shin Su-Jin SJ Choe Eun-Ah EA Kim Jungyoun J Hyung Woo Jin WJ Kim Hyo Song HS Jung Minkyu M Beom Seung-Hoon SH Kim Tae Il TI Ahn Joong Bae JB Chung Hyun Cheol HC Shin Sang Joon SJ
Cancers 20220527 11
The canonical mutations in gastrointestinal stromal tumors (GISTs) are typically activating mutations in <i>KIT</i> and platelet-derived growth factor receptor alpha (PDGFRA). GISTs with non-canonical mutations are a heterogeneous group. Here, we examined tropomyosin-related kinase (TRK) fusion in GIST cases without <i>KIT/PDGFRA</i> mutations (<i>KIT/PDGFRA</i> wild-type (WT) GISTs). We retrospectively analyzed patients who were diagnosed with GISTs at the Yonsei Cancer Center, Severance Hospit ...[more]