Associations of systemic inflammation markers with identification of pulmonary nodule and incident lung cancer in Chinese population.

ABSTRACT:

Objectives

Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII), easily accessible systemic inflammation response parameters, were reported to associate with poor lung cancer prognosis. However, research on the effects of these markers on the risk of positive nodules (PNs) and lung cancer is limited.

Methods

Participants in this retrospective study were those who had their first computed tomography (CT) screening at Jiangsu Province Hospital's Health Promotion Center between January 1, 2017 and December 31, 2020. We identified PNs (≥6 mm in diameter) from free text of CT reports and lung cancer from medical records. Multivariate logistic analysis was used to assess the association between NLR, PLR, or SII and

SUBMITTER: Tian T 

PROVIDER: S-EPMC9189452 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature