Ontology highlight
ABSTRACT:
SUBMITTER: Kiaie SH
PROVIDER: S-EPMC9194786 | biostudies-literature | 2022 Jun
REPOSITORIES: biostudies-literature
Journal of nanobiotechnology 20220614 1
In the last decade, the development of messenger RNA (mRNA) therapeutics by lipid nanoparticles (LNP) leads to facilitate clinical trial recruitment, which improves the efficacy of treatment modality to a large extent. Although mRNA-LNP vaccine platforms for the COVID-19 pandemic demonstrated high efficiency, safety and adverse effects challenges due to the uncontrolled immune responses and inappropriate pharmacological interventions could limit this tremendous efficacy. The current study reveal ...[more]