Ontology highlight
ABSTRACT:
SUBMITTER: Song Q
PROVIDER: S-EPMC9214843 | biostudies-literature | 2022 Jun
REPOSITORIES: biostudies-literature
RSC advances 20220622 28
To explore the mechanism of silver and rhodium catalysis and reveal the origin of the chemo- and enantioselectivity of the reaction, density functional theory calculations were performed on the first silver-catalyzed highly enantioselective carbene transfer reaction. The calculation results reveal that when silver is used as a catalyst, due to the participation of the phosphate anion in the transition state, the enhanced nucleophilicity of the α-diazoacetamide unit promotes smooth dearomatizatio ...[more]