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A SARS-Cov-2 sensor based on upconversion nanoparticles and graphene oxide.

ABSTRACT: Since the beginning of the COVID-19 pandemic, there has been an increased need for the development of novel diagnostic solutions that can accurately and rapidly detect SARS-CoV-2 infection. In this work, we demonstrate the targeting of viral oligonucleotide markers within minutes without the requirement of a polymerase chain reaction (PCR) amplification step via the use of oligonucleotide-coated upconversion nanoparticles (UCNPs) and graphene oxide (GO).

SUBMITTER: Alexaki K

PROVIDER: S-EPMC9215703 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature

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A SARS-Cov-2 sensor based on upconversion nanoparticles and graphene oxide.

Alexaki Konstantina K Kyriazi Maria Eleni ME Greening Joshua J Taemaitree Lapatrada L El-Sagheer Afaf H AH Brown Tom T Zhang Xunli X Muskens Otto L OL Kanaras Antonios G AG

RSC advances 20220622 29

Since the beginning of the COVID-19 pandemic, there has been an increased need for the development of novel diagnostic solutions that can accurately and rapidly detect SARS-CoV-2 infection. In this work, we demonstrate the targeting of viral oligonucleotide markers within minutes without the requirement of a polymerase chain reaction (PCR) amplification step <i>via</i> the use of oligonucleotide-coated upconversion nanoparticles (UCNPs) and graphene oxide (GO). ...[more]

PMID: 35799935

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