Ontology highlight
ABSTRACT:
SUBMITTER: Torices S
PROVIDER: S-EPMC9216729 | biostudies-literature | 2022 Jun
REPOSITORIES: biostudies-literature
Torices Silvia S Motta Carolline C da Rosa Barbara B Marcos Anne A Alvarez-Rosa Liandra L Siqueira Michele M Moreno-Rodriguez Thaidy T Matos Aline A Caetano Braulia B Martins Jessica J Gladulich Luis L Loiola Erick E Bagshaw Olivia O Stuart Jeffrey J Siqueira Marilda M Stipursky Joice J Toborek Michal M Adesse Daniel D
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Neurological effects of COVID-19 and long-COVID-19 as well as neuroinvasion by SARS-CoV-2 still pose several questions and are of both clinical and scientific relevance. We described the cellular and molecular effects of the human brain microvascular endothelial cells (HBMECs) <i>in vitro</i> infection by SARS-CoV-2 to understand the underlying mechanisms of viral transmigration through the Blood-Brain Barrier. Despite the low to non- productive viral replication, SARS-CoV-2-infected cultures di ...[more]