Early Onset Diffusion Abnormalities in Refractory Headache Disorders.

ABSTRACT:

Objective

This study sought to determine if individuals with medically refractory migraine headache have volume or diffusion abnormalities on neuroimaging compared to neurotypical individuals.

Background

Neuroimaging biomarkers in headache medicine continue to be limited. Early prediction of medically refractory headache and migraine disorders could result in earlier administration of high efficacy therapeutics.

Methods

A single-center, retrospective, case control study was performed. All patients were evaluated clinically between 2014 and 2018. Individuals with medically refractory migraine headache (defined by ICDH-3 criteria) without any other chronic medical diseases were enrolled. Patients had to have failed more than two therapeutics and aura was not exclusionar

SUBMITTER: Santoro JD 

PROVIDER: S-EPMC9237368 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature