Clinical outcome of non-alcoholic fatty liver disease: an 11-year follow-up study.

ABSTRACT:

Objectives

To clarify non-alcoholic fatty liver disease (NAFLD) prevalence, risk factors and clinical outcome in an exemplary Chinese population, a cohort of company employees was followed up for 11 years.

Design

Retrospective cohort study.

Setting

Between 2006 and 2016 in Ning bo, China.

Participants

13 032 company employees.

Results

Over 11 years, the prevalence of NAFLD increased from 17.2% to 32.4% (men 20.5%-37% vs women 9.8%-22.2%). Male peak prevalence was between 40 and 60 years of age, whereas highest prevalence in women was at an age of 60 years and older. Logistic and Cox regression revealed 16 risk factors, including body mass index (BMI), albumin, white blood cell, triglycerides (TG), high-density lipoprotein, glutamyl transpeptidase, alanin

SUBMITTER: Tang X 

PROVIDER: S-EPMC9237861 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature