The potential shared brain functional alterations between adults with ADHD and children with ADHD co-occurred with disruptive behaviors.

ABSTRACT:

Background

Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder. Many previous studies have shown that the comorbid status of disruptive behaviour disorders (DBD) was a predictor for ADHD persistence into adulthood. However, the brain mechanisms underlying such a relationship remain unclear. Thus, we aim to investigate whether the brain functional alteration in adults with ADHD could also be detected in children with ADHD co-occurring with disruptive behaviours from both quantitative and categorical dimensions.

Methods

A total of 172 children with ADHD (cADHD), 98 adults with ADHD (aADHD), 77 healthy control children (cHC) and 40 healthy control adults (aHC) were recruited. The whole-brain spontaneous fluctuations in brain activity of each

SUBMITTER: Liu N 

PROVIDER: S-EPMC9238266 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature