Ontology highlight
ABSTRACT: Clinical trial registration
www.ClinicalTrials.gov, identifier: NCT01853124.
SUBMITTER: Horne RG
PROVIDER: S-EPMC9238408 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Horne Rachael G RG Freedman Stephen B SB Johnson-Henry Kathene C KC Pang Xiao-Li XL Lee Bonita E BE Farion Ken J KJ Gouin Serge S Schuh Suzanne S Poonai Naveen N Hurley Katrina F KF Finkelstein Yaron Y Xie Jianling J Williamson-Urquhart Sarah S Chui Linda L Rossi Laura L Surette Michael G MG Sherman Philip M PM
Frontiers in cellular and infection microbiology 20220614
Compositional analysis of the intestinal microbiome in pre-schoolers is understudied. Effects of probiotics on the gut microbiota were evaluated in children under 4-years-old presenting to an emergency department with acute gastroenteritis. Included were 70 study participants (n=32 placebo, n=38 probiotics) with stool specimens at baseline (day 0), day 5, and after a washout period (day 28). Microbiota composition and deduced functions were profiled using 16S ribosomal RNA sequencing and predict ...[more]