The profile of HDL-C subfractions and their association with cardiovascular risk in the Hungarian general and Roma populations.

ABSTRACT: High-density lipoprotein cholesterol (HDL-C) is not a homogenous lipid fraction, but it can be further divided into subfractions. It is well-known that the Roma population has a high prevalence of reduced HDL-C levels and cardiovascular diseases (CVDs). However, it is unknown how this reduction affects different HDL subfractions, and whether changes in their quantity/representation are associated with an increased cardiovascular risk among them. In the present study, the HDL subfraction profile of the Hungarian general (HG) and the Roma populations were compared, and the subfractions showing a significant difference between the two populations were identified. The association of HDL subfractions with CVD risk estimated by the Framingham risk score (FRS) and the Systematic COronary Risk Eva

SUBMITTER: Piko P 

PROVIDER: S-EPMC9240088 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature