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Neutral Red-carbon nanodots for selective fluorescent DNA sensing.


ABSTRACT: Carbon nanodots modified with Neutral Red covalently inserted in the nanostructure (NR-CDs) have been prepared by a simple synthesis method based on microwave irradiation under controlled temperature and pressure. The synthetized NR-CDs have been characterized by different techniques, demonstrating the covalent bonding of Neutral Red molecules to the carbon dots nanostructure. Fluorescence activity of the prepare NR-CDs has been explored showing different interaction pathways with singled and doubled stranded DNA. These studies have been successfully applied to develop a new fluorescence DNA hybridization assay to the detection of a specific DNA sequence of Escherichia coli bacteria.

SUBMITTER: Martinez-Perinan E 

PROVIDER: S-EPMC9242914 | biostudies-literature |

REPOSITORIES: biostudies-literature

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