Non-prostate cancer tumours: incidence on ¹⁸F-DCFPyL PSMA PET/CT and uptake characteristics in 1445 patients.

ABSTRACT:

Purpose

With increasing use of PSMA PET/CT in the staging and restaging of prostate cancer (PCa), the identification of non-prostate cancer tumours (NPCaT) has become an increasing clinical dilemma. Atypical presentations of PSMA expression in prostate cancer and expression in NPCaT are not well established. Understanding the normal and abnormal distribution of PSMA expression is essential in preparing clinically relevant reports and in guiding multidisciplinary discussion and decisions.

Methods

Retrospective review of 1445 consecutive ¹⁸F-DCFPyL PSMA PET/CT studies by experienced radiologists and nuclear medicine physicians. Lesions indeterminate for PCa were identified. Correlation was made with patient records, biopsy results, and dedicated imaging. Lesions wer

SUBMITTER: Perry E 

PROVIDER: S-EPMC9250467 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature