Dataset Information

Recovery of functional fitness, lung function and immune function in health care workers with non-severe and severe COVID-19 at 13 months after discharge from the hospital: a prospective cohort study.

ABSTRACT:

Objective

This study aimed to evaluate the recovery of functional fitness, lung function and immune function in HCWs with non-severe and severe COVID-19 at 13 months after discharge from the hospital.

Methods

The participants of "Rehabilitation Care Project for Medical Staff Infected with COVID-19" underwent functional fitness test (muscle strength, flexibility and agility/dynamic balance), lung function test and immune function test (including cytokines and lymphocyte subsets) at 13 months after discharge.

Results

The project included 779 HCWs (316 non-severe COVID-19 and 463 severe COVID-19). This study found 29.1% (130/446) of the HCWs as not yet recovered their functional fitness. The most affected lung function indicator was lung perfusion capacity (34% with DLCO-SB <80%). The increase of IL-6 (64/534, 12.0%) and NK cells (44/534, 8.2%), decrease of CD3⁺ T cells (58/534, 10.9%) and CD4⁺ T cells (26/534, 4.9%) still existed at 13 months after discharge. No significant difference was found in the HCWs with non-severe and severe COVID-19 regarding recovery of functional fitness, lung function and immune function at 13 months after discharge.

Conclusions

The majority of Chinese HCWs with COVID-19 had recovered their functional fitness, lung function, and immune function, and the recovery status in HCWs with severe COVID-19 is no worse than that in HCWs with non-severe COVID-19 at 13 months after discharge from the hospital.

SUBMITTER: Xiong L

PROVIDER: S-EPMC9250704 | biostudies-literature |

REPOSITORIES: biostudies-literature

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