Ontology highlight
ABSTRACT:
SUBMITTER: Cretin G
PROVIDER: S-EPMC9252838 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
Cretin Gabriel G Galochkina Tatiana T Vander Meersche Yann Y de Brevern Alexandre G AG Postic Guillaume G Gelly Jean-Christophe JC
Nucleic acids research 20220701 W1
Understanding the functions and origins of proteins requires splitting these macromolecules into fragments that could be independent in terms of folding, activity, or evolution. For that purpose, structural domains are the typical level of analysis, but shorter segments, such as subdomains and supersecondary structures, are insightful as well. Here, we propose SWORD2, a web server for exploring how an input protein structure may be decomposed into 'Protein Units' that can be hierarchically assem ...[more]