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Acute kidney injury in infants with congenital diaphragmatic hernia.


ABSTRACT:

Objectives

To assess the incidence of acute kidney injury (AKI) in infants with congenital diaphragmatic hernia (CDH), including those who had fetoscopic endoluminal tracheal occlusion (FETO), and the effect of AKI on mortality and length of stay.

Study design

Ten-year retrospective review of infants admitted with CDH to a tertiary perinatal centre.

Result

Ninety-four infants with median gestational age of 38+1 weeks were included. Fifty-nine (62.8%) infants had AKI. Compared to infants without AKI, infants with AKI, had a similar incidence of mortality (p = 0.989). In survivors, AKI was not independently associated with a longer adjusted median length of stay [23 versus 15 days (p = 0.194)]. FETO was associated with an increased risk of AKI (p = 0.005), but neither the mortality nor length of stay of FETO infants who had AKI was increased.

Conclusion

AKI was present in the majority of infants with CDH and most common in those who had undergone FETO.

SUBMITTER: Arattu Thodika FMS 

PROVIDER: S-EPMC9259479 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature

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Publications

Acute kidney injury in infants with congenital diaphragmatic hernia.

Arattu Thodika Fahad M S FMS   Dassios Theodore T   Deep Akash A   Greenough Anne A  

Journal of perinatology : official journal of the California Perinatal Association 20220407 7


<h4>Objectives</h4>To assess the incidence of acute kidney injury (AKI) in infants with congenital diaphragmatic hernia (CDH), including those who had fetoscopic endoluminal tracheal occlusion (FETO), and the effect of AKI on mortality and length of stay.<h4>Study design</h4>Ten-year retrospective review of infants admitted with CDH to a tertiary perinatal centre.<h4>Result</h4>Ninety-four infants with median gestational age of 38<sup>+1</sup> weeks were included. Fifty-nine (62.8%) infants had  ...[more]

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