State and Trait Anxiety Share Common Network Topological Mechanisms of Human Brain.

ABSTRACT: Anxiety is a future-oriented unpleasant and negative mental state induced by distant and potential threats. It could be subdivided into momentary state anxiety and stable trait anxiety, which play a complex and combined role in our mental and physical health. However, no studies have systematically investigated whether these two different dimensions of anxiety share a common or distinct topological mechanism of human brain network. In this study, we used macroscale human brain morphological similarity network and functional connectivity network as well as their spatial and temporal variations to explore the topological properties of state and trait anxiety. Our results showed that state and trait anxiety were both negatively correlated with the coefficient of variation of nodal efficiency

SUBMITTER: Li Y 

PROVIDER: S-EPMC9260038 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature