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Intrathecal daptomycin use in a challenging case of Enterococcus faecium ventriculitis.

ABSTRACT: Treatment of ventriculitis caused by enterococci can be challenging, and antibiotic options are limited. We describe a case of device-related ventriculitis caused by vancomycin-resistant Enterococcus faecium , refractory to initial antibiotics. Our management approach included intrathecal daptomycin. There were no attributable adverse events, and the patient remained infection-free following ventriculo-peritoneal shunt insertion and cessation of antibiotics.

SUBMITTER: Dhariwal A

PROVIDER: S-EPMC9260094 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature

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Intrathecal daptomycin use in a challenging case of Enterococcus faecium ventriculitis.

Dhariwal Ankush A Leff Rachel R Allen Mike M Cherian Benny B

Access microbiology 20220408 4

Treatment of ventriculitis caused by enterococci can be challenging, and antibiotic options are limited. We describe a case of device-related ventriculitis caused by vancomycin-resistant Enterococcus faecium , refractory to initial antibiotics. Our management approach included intrathecal daptomycin. There were no attributable adverse events, and the patient remained infection-free following ventriculo-peritoneal shunt insertion and cessation of antibiotics. ...[more]

PMID: 35812713

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