Organic extract of Geodia cydonium induces cell cycle block in human mesothelioma cells.

ABSTRACT: The serious side effects caused by chemotherapeutics and the development of cancer chemoresistance represent the most significant limitations in the treatment of cancer. Some alternative approaches have been developed in recent years, which are based on natural compounds, and have allowed important advances in cancer therapeutics. During the last 50 years, sponges have been considered a promising source of natural products from the marine environment, representing ~30% of all marine natural products. Among sponges, the Mediterranean species Geodia cydonium represents a potential source of these type of products with considerable biotechnological interest as pharmaceutical agents. The present study demonstrated the antiproliferative effect of an organic G. cydonium extract (GE

SUBMITTER: Di Meo F 

PROVIDER: S-EPMC9260718 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature