Relationship between cognitive functioning and frailty in older breast cancer survivors.

ABSTRACT:

Introduction

The relationship between cognitive function and frailty in older, long-term breast cancer survivors was examined.

Materials and methods

Breast cancer survivors who were diagnosed and treated at 60 years of age or above and were 5-15 year disease-free survivors and non-cancer controls matched on age and education were evaluated with neuropsychological tests and the Comprehensive Geriatric Assessment which was used to assess frailty based on a deficit accumulation frailty index (DAFI).

Results

Unadjusted regression analyses revealed that cancer survivors scored significantly lower on the Language (P = 0.015), Attention, Processing Speed, Executive Function (APE) (P = 0.015), and Learning and Memory (LM) (P = 0.023) domains compared to controls. However, onl

SUBMITTER: Ahles TA 

PROVIDER: S-EPMC9262141 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature