Lactococcus lactis KF140 Reduces Dietary Absorption of N^ε - (Carboxymethyl)lysine in Rats and Humans via β-Galactosidase Activity.

ABSTRACT:

Background and aims

Excessive intake of advanced glycation end products (AGEs), which are formed in foods cooked at high temperatures for long periods of time, has negative health effects, such as inflammatory responses and oxidative stress. N^ε-(Carboxymethyl)lysine (CML) is one of the major dietary AGEs. Given their generally recognized as safe status and probiotic functionalities, lactic acid bacteria may be ideal supplements for blocking intestinal absorption of food toxicants. However, the protective effects of lactic acid bacteria against dietary AGEs have not been fully elucidated.

Materials and methods

We investigated the effect of treatment with Lactococcus lactis KF140 (LL-KF140), which was isolated from kimchi, on the levels and toxicokinetics of

SUBMITTER: Park HY 

PROVIDER: S-EPMC9263842 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature