Ontology highlight
ABSTRACT:
SUBMITTER: Guiberson ER
PROVIDER: S-EPMC9264265 | biostudies-literature | 2022 Jun
REPOSITORIES: biostudies-literature
Guiberson Emma R ER Good Christopher J CJ Wexler Aaron G AG Skaar Eric P EP Spraggins Jeffrey M JM Caprioli Richard M RM
Journal of the American Society for Mass Spectrometry 20220511 6
The gastrointestinal tract, including luminal content, harbors a complex mixture of microorganisms, host dietary content, and immune factors. Existing imaging approaches remove luminal content and only visualize small regions of the GI tract. Here, we demonstrate a workflow for multimodal imaging using matrix-assisted laser desorption/ionization imaging mass spectrometry, autofluorescence, and bright field microscopy for mapping intestinal tissue and luminal content. Results comparing tissue and ...[more]