Ontology highlight
ABSTRACT:
SUBMITTER: Xiao Q
PROVIDER: S-EPMC9266783 | biostudies-literature | 2022 Jun
REPOSITORIES: biostudies-literature
Xiao Qingjie Q Xu Mengxue M Wang Weiwei W Wu Tingting T Zhang Weizhe W Qin Wenming W Sun Bo B
International journal of molecular sciences 20220629 13
The major facilitator superfamily (MFS) is the largest secondary transporter family and is responsible for transporting a broad range of substrates across the biomembrane. These proteins are involved in a series of conformational changes during substrate transport. To decipher the transport mechanism, it is necessary to obtain structures of these different conformations. At present, great progress has been made in predicting protein structure based on coevolutionary information. In this study, A ...[more]