Zinc and Breast Cancer Survival: A Prospective Cohort Study of Dietary Intake and Serum Levels.

ABSTRACT: Zinc has been suggested to play a role in breast cancer progression; however, no previous study on zinc levels and the potential effect on breast cancer survival has been conducted. This study investigates recurrence-free survival (RFS), breast cancer-specific survival (BCSS) and overall survival (OS) in relation to zinc levels, in serum and diet, overall and stratified for phosphorus and selenium levels. The Malmö Diet and Cancer Study, a prospective population-based cohort in Sweden including 17,035 women, was used to identify breast cancer patients diagnosed in the period 1991-2013. Diet was assessed by a validated modified diet history method. A Cox regression analysis yielded hazard ratios (HRs) with 95% confidence intervals adjusted for potential confounders. Out of 1062 patients wit

SUBMITTER: Bengtsson Y 

PROVIDER: S-EPMC9268140 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature